Endocrine Abstracts

The diagnosis of Cushing’s syndrome (CS) is based primarily on diagnostic tests evaluating the cortisol response to dexamethasone suppression. Tests based on oral administration of dexamethasone may be compromised by poor compliance. We evaluated the diagnostic accuracy of a novel intravenous dexamethasone suppression test (IDST). The test is performed by intravenous (iv) bolus injection of 8 mg dexamethasone, with blood cortisol determinations made before injection, then...

Introduction: IPSS (Inferior petrosal sinus sampling) is a reliable test for differentiating Cushing’s disease from ectopic ACTH secretion. In the past 30 years, Hadassah Hebrew University Hospital has been the sole national referral center for IPSS in Israel, carrying out the test for all patients country-wide.Methods: In this retrospective study we reviewed the records of all patients who underwent IPSS in our institution, for whom electronic dat...